Purified Anti-Human CD178 Antibody[NOK-1] (AN009640P)

Name: Purified Anti-Human CD178 Antibody[NOK-1]
Brand: Elabscience
SKU: AN009640P
Price: 20.0 USD
Availability: InStock

Copy the product info.

Citations ({{ citationsPage.numTotal }}) Manual MSDS

Spectrum viewer

Cell Markers

Purified Anti-Human CD178 Antibody[NOK-1] - 1

All	Size	Price	Qty
	100μg	$ 50.00	- +
	25μg	$ 20.00	- +

Bulk request

Add to cart

For research use only. Order now, ship in 3 days

Conjugation: Unconjugated

Unconjugated Show More Show Less

Inquire about other conjugation options

Alternate Names	Apoptosis (APO 1) antigen ligand 1, Apoptosis antigen ligand 1, CD95 ligand, CD95L protein, Fas L, Fas ligand (TNF superfamily member 6), Fasl Fas ligand (TNF superfamily member 6), Generalized lymphoproliferative disease, Gld, soluble form, TNFL6, Tumor necrosis factor (ligand) superfamily member 6, apoptosis(APO-1) antigen ligand, apoptosis (APO-1) antigen ligand, tumor necrosis factor ligand superfamily member, TNFSF, APT1LG, FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6, TNLG1A, Fas ligand, Apo I Ligand, apoptosis (APO-1) antigen ligand 1, Fas ligand (TNF superfamily, member 6), soluble Fas Ligand (sFasL), APT1LG1CD95L, TNFSF6FasL, apoptosis(APO-1) antigen ligand 1, Apoptosis antigen ligand, CD178 antigen, Fas antigen ligand, FASLCD95 ligand, tumor necrosis factor ligand superfamily member 6, CD95L, TNFSF6
Clone	NOK-1
Verified Samples	Verified Samples in FCM: HEK293T cells transfected with pcDNA3.1 plasmid encoding Human CD178 gene
Dilution	FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)
Background	Fas Ligand (FasL), also known as CD178, CD95L, or TNFSF6, is a transmembrane protein homotrimer that binds to Fas/CD95 and triggers apoptosis in the Fas-expressing cell. Fas Ligand also binds the soluble decoy receptor DcR3. It is expressed on activated Th1 cells, CD8+ cytotoxic T cells, and NK cells. A soluble form can be released which remains trimeric and retains the ability to bind Fas. Fas Ligand-induced apoptosis plays a central role in the development of immune tolerance and the maintance of immune privileged sites. Tumor cells can evade immune surveillance by upregulating Fas Ligand to kill tumor infiltrating lymphocytes. In gld mice, a Fas Ligand point mutation is the cause of severe lymphoproliferation and systemic autoimmunity.
Immunogen	Recombinant Human CD178 protein
Abbre	CD178
Swissprot	P48023
Host	Mouse
Reactivity	Human
Clonality	Monoclonal
Purification Method	>98%, Protein A/G purified
Isotype	Mouse IgG1, κ
Isotype Control	Purified Mouse IgG1, κ Isotype Control[MOPC-21]
Applications	FCM
Research Areas	Stem Cells;Immunology;Cell Biology;Cytokine and Growth Factors;Mitochondrial Pathway;Death Receptors Signaling Pathway;CDs;Hematopoietic Stem Cell Markers
Cellular Localization	Cell membrane, Secreted
Concentration	≥ 1 mg/mL
Conjugation	Unconjugated
Storage Buffer	Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Storage	Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Expiration Date	12 months
Shipping	Ice bag